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KMID : 0364819880260040355
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Korean Journal of Microbiology
1988 Volume.26 No. 4 p.355 ~ p.361
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Relationship between Sprulation and Synthesis of Alkaline Protease in Streptomyces sp.
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Jeong, Byeong Chul/정병철
Shin, Hyun Seung/Lee, Kye Joon/신현승/이계준
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Abstract
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1
The aims of the present studies were to understand the physiolosical and genetic characters of Streptomyces sp. Isolated from soil. It revealed that Streptomyces sp. SMF3tl1 had very fast growth rate and produced eatracefalar protease and heavily sporulated on rich media. It also showed ft-lactamase activity and pigment production. Noasporulatiag mutants were isolated after NTG or acriflavin treatment and their characters were compared with the parent strain. It was found that the mutants obtained by acriflavin treatment and their characters were compared with the parent strain. It was found that the mutants obtained by acriflavm treatment lost the pigment formation and 4-lactamase production. Protease activity of the mutant was lowered and the pH optimum was changed toward neutral. It was found that the changes were resulted from the reduction of alkaline protease biosynthesis in the bald mutant. Therefore it is considered that sporolatlon, pigment formation, P-iactamase production, and alkaline protease production in Streptomyces sp. might be controlled with a closely related relationship.
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